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Estrogen Receptor-α Mediates the Epidermal Growth Factor-Stimulated Prolactin Expression and Release in Lactotrophs
Epidermal growth factor (EGF) is a potent regulator of cell function in many cell types. EGF-receptor (EGFR/ErbB1)-activated Erk1/2 has been reported to activate estrogen receptor (ER) in an estrogen (E2)-independent manner. In the pituitary lactotrophs, both EGF and E2 stimulate prolactin (PRL) rel...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The Endocrine Society
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646526/ https://ncbi.nlm.nih.gov/pubmed/18832099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0756 |
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