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Attenuation of Endocrine-Exocrine Pancreatic Communication in Type 2 Diabetes: Pancreatic Extracellular Matrix Ultrastructural Abnormalities

Ultrastructural observations reveal a continuous interstitial matrix connection between the endocrine and exocrine pancreas, which is lost due to fibrosis in rodent models and humans with type 2 diabetes mellitus (T2DM). Widening of the islet exocrine interface (IEI) appears to result in loss of des...

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Main Authors: Hayden, Melvin R, Patel, Kamlesh, Habibi, Javad, Gupta, Deepa, Tekwani, Seema S., Whaley-Connell, Adam, Sowers, James R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646502/
https://ncbi.nlm.nih.gov/pubmed/19040593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1559-4572.2008.00024.x
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