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Leveraging existing biological knowledge in the identification of candidate genes for facial dysmorphology

BACKGROUND: In response to the frequently overwhelming output of high-throughput microarray experiments, we propose a methodology to facilitate interpretation of biological data in the context of existing knowledge. Through the probabilistic integration of explicit and implicit data sources a functi...

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Autori principali: Tipney, Hannah J, Leach, Sonia M, Feng, Weiguo, Spritz, Richard, Williams, Trevor, Hunter, Lawrence
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646237/
https://ncbi.nlm.nih.gov/pubmed/19208187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S2-S12
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