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Moderate Dietary Vitamin B-6 Restriction Raises Plasma Glycine and Cystathionine Concentrations While Minimally Affecting the Rates of Glycine Turnover and Glycine Cleavage in Healthy Men and Women

Glycine is a precursor of purines, protein, glutathione, and 1-carbon units as 5,10-methylenetetrahydrofolate. Glycine decarboxylation through the glycine cleavage system (GCS) and glycine-serine transformation by serine hydroxymethyltransferase (SHMT) require pyridoxal 5′-phosphate (PLP; active for...

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Detalhes bibliográficos
Main Authors: Lamers, Yvonne, Williamson, Jerry, Ralat, Maria, Quinlivan, Eoin P., Gilbert, Lesa R., Keeling, Christine, Stevens, Robert D., Newgard, Christopher B., Ueland, Per M., Meyer, Klaus, Fredriksen, Ase, Stacpoole, Peter W., Gregory, Jesse F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646220/
https://ncbi.nlm.nih.gov/pubmed/19158217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.108.099184
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