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Role of B cells in Systemic Lupus Erythematosus and Rheumatoid Arthritis

B cell tolerance to many self-proteins is actively maintained by either purging self-reactive B receptors through clonal deletion and receptor editing, or by functional silencing known as anergy. However, these processes are clearly incomplete as B cell-driven autoimmune diseases still occur. The si...

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Detalhes bibliográficos
Main Authors: Mandik-Nayak, Laura, Ridge, Natalie, Fields, Michele, Park, Audrey Y., Erikson, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646198/
https://ncbi.nlm.nih.gov/pubmed/18775493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.08.003
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