Crucial Role of the CB3-Region of Collagen IV in PARF-Induced Acute Rheumatic Fever

Acute rheumatic fever (ARF) and rheumatic heart disease are serious autoimmune sequelae to infections with Streptococcus pyogenes. Streptococcal M-proteins have been implicated in ARF pathogenesis. Their interaction with collagen type IV (CIV) is a triggering step that induces generation of collagen...

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Main Authors: Dinkla, Katrin, Talay, Susanne R., Mörgelin, Matthias, Graham, Rikki M. A., Rohde, Manfred, Nitsche-Schmitz, D. Patric, Chhatwal, Gursharan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646144/
https://ncbi.nlm.nih.gov/pubmed/19252743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004666
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