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Structure of the sulphiredoxin–peroxiredoxin complex reveals an essential repair embrace
Typical 2-Cys peroxiredoxins (Prxs) have an important role in regulating hydrogen peroxide-mediated cell signalling1. In this process, Prxs can become inactivated through the hyperoxidation of an active site Cys residue to Cys sulphinic acid. The unique repair of this moiety by sulphiredoxin (Srx) r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646140/ https://ncbi.nlm.nih.gov/pubmed/18172504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06415 |
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