Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors

Acting through a number of distinct pathways, many G protein-coupled receptors (GPCRs) activate the extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) cascade. Recently, it has been shown that in some cases, clathrin-mediated endocytosis is required for GPCR activati...

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Bibliografiske detaljer
Main Authors: Pierce, Kristen L., Maudsley, Stuart, Daaka, Yehia, Luttrell, Louis M., Lefkowitz, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26461/
https://ncbi.nlm.nih.gov/pubmed/10677489
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