Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

OBJECTIVE—Insulin secretion involves complex events in which the mitochondria play a pivotal role in the generation of signals that couple glucose detection to insulin secretion. Studies on the mitochondrial generation of reactive oxygen species (ROS) generally focus on chronic nutrient exposure. He...

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Detalhes bibliográficos
Main Authors: Leloup, Corinne, Tourrel-Cuzin, Cécile, Magnan, Christophe, Karaca, Melis, Castel, Julien, Carneiro, Lionel, Colombani, Anne-Laure, Ktorza, Alain, Casteilla, Louis, Pénicaud, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646066/
https://ncbi.nlm.nih.gov/pubmed/19073765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1056
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