Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

OBJECTIVE—Insulin secretion involves complex events in which the mitochondria play a pivotal role in the generation of signals that couple glucose detection to insulin secretion. Studies on the mitochondrial generation of reactive oxygen species (ROS) generally focus on chronic nutrient exposure. He...

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Main Authors: Leloup, Corinne, Tourrel-Cuzin, Cécile, Magnan, Christophe, Karaca, Melis, Castel, Julien, Carneiro, Lionel, Colombani, Anne-Laure, Ktorza, Alain, Casteilla, Louis, Pénicaud, Luc
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
Teme:
Islet Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646066/
https://ncbi.nlm.nih.gov/pubmed/19073765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1056
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