Elevated Levels of the Anti-Inflammatory Interleukin-1 Receptor Antagonist Precede the Onset of Type 2 Diabetes: The Whitehall II Study

OBJECTIVE—Interleukin-1 receptor antagonist (IL-1Ra), a natural inhibitor of interleukin-1β, has been shown to improve β-cell function and glycemic control in patients with type 2 diabetes. The aim of this study was to investigate whether baseline systemic levels of IL-1Ra are associated with incide...

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Detalhes bibliográficos
Main Authors: Herder, Christian, Brunner, Eric J., Rathmann, Wolfgang, Strassburger, Klaus, Tabák, Adam G., Schloot, Nanette C., Witte, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Epidemiology/Health Services Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646020/
https://ncbi.nlm.nih.gov/pubmed/19073760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc08-1161
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