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Posttranscriptional Regulation of p53 and Its Targets by RNA-Binding Proteins

p53 tumor suppressor plays a pivotal role in maintaining genomic integrity and preventing cancer development. The importance of p53 in tumor suppression is illustrated by the observation that about 50% human tumor cells have a dysfunctional p53 pathway. Although it has been well accepted that the ac...

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Detalhes bibliográficos
Main Authors: Zhang, Jin, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646002/
https://ncbi.nlm.nih.gov/pubmed/19075680
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