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New Strategy for Quantifying Biological Zinc by a Modified Zinpyr Fluorescence Sensor

[Image: see text] Substitution of one pyridine by pyrazine in each DPA appendage of ZP1, leads to a new zinc sensor, ZPP1, with a modified background fluorescence and zinc affinity. ZPP1 exhibits a two-step zinc response during fluorescence titrations, which leads to a new method for zinc quantifica...

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Detalhes bibliográficos
Main Authors: Zhang, Xiao-an, Hayes, Dugan, Smith, Sarah J., Friedle, Simone, Lippard, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645955/
https://ncbi.nlm.nih.gov/pubmed/18975868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807156b
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