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Sequence context-specific profiles for homology searching

Sequence alignment and database searching are essential tools in biology because a protein's function can often be inferred from homologous proteins. Standard sequence comparison methods use substitution matrices to find the alignment with the best sum of similarity scores between aligned resid...

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Détails bibliographiques
Auteurs principaux: Biegert, A., Söding, J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645910/
https://ncbi.nlm.nih.gov/pubmed/19234132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810767106
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