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The SIRT2 Deacetylase Regulates Autoacetylation of p300

Autoacetylation of the p300 histone acetyltransferase controls the transition between VP16-mediated chromatin acetylation and preinitiation complex (PIC) assembly. Currently, it is unknown if and how autoacetylated p300 is deacetylated. We found that the NAD(+)-dependent histone deacetylase SIRT2 de...

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Detalhes bibliográficos
Main Authors: Black, Joshua C., Mosley, Amber, Kitada, Tasuku, Washburn, Michael, Carey, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645867/
https://ncbi.nlm.nih.gov/pubmed/18995842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.09.018
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