MsrB1 (Methionine-R-sulfoxide Reductase 1) Knock-out Mice: ROLES OF MsrB1 IN REDOX REGULATION AND IDENTIFICATION OF A NOVEL SELENOPROTEIN FORM

Protein oxidation has been linked to accelerated aging and is a contributing factor to many diseases. Methionine residues are particularly susceptible to oxidation, but the resulting mixture of methionine R-sulfoxide (Met-RO) and methionine S-sulfoxide (Met-SO) can be repaired by thioredoxin-depende...

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Detalles Bibliográficos
Autores principales: Fomenko, Dmitri E., Novoselov, Sergey V., Natarajan, Sathish Kumar, Lee, Byung Cheon, Koc, Ahmet, Carlson, Bradley A., Lee, Tae-Hyung, Kim, Hwa-Young, Hatfield, Dolph L., Gladyshev, Vadim N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Synthesis, Post-Translational Modification, and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645841/
https://ncbi.nlm.nih.gov/pubmed/18990697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805770200
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