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Normal Hepatic Cell Surface Localization of the High Density Lipoprotein Receptor, Scavenger Receptor Class B, Type I, Depends on All Four PDZ Domains of PDZK1

PDZK1 is a four PDZ domain-containing scaffold protein that binds to scavenger receptor class B, type I (SR-BI), the high density lipoprotein receptor, by its first PDZ domain (PDZ1). PDZK1 knock-out mice exhibit a >95% decrease in hepatic SR-BI protein and consequently an ∼70% increase in plasma...

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Bibliografische gegevens
Hoofdauteurs: Fenske, Sara A., Yesilaltay, Ayce, Pal, Rinku, Daniels, Kathleen, Barker, Caroline, Quiñones, Verónica, Rigotti, Attilio, Krieger, Monty, Kocher, Olivier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645830/
https://ncbi.nlm.nih.gov/pubmed/19116202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808211200
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