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DNA methyltransferase 1o functions during preimplantation development to preclude a profound level of epigenetic variation
Most mouse embryos developing in the absence of the oocyte-derived DNA methyltransferase 1o (DNMT1o-deficient embryos) have significant delays in development and a wide range of anatomical abnormalities. To understand the timing and molecular basis of such variation, we studied pre- and post-implant...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645800/ https://ncbi.nlm.nih.gov/pubmed/18845137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.015 |
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