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Temporally-Controlled Site-Specific Recombination in Zebrafish

Conventional use of the site-specific recombinase Cre is a powerful technology in mouse, but almost absent in other vertebrate model organisms. In zebrafish, Cre-mediated recombination efficiency was previously very low. Here we show that using transposon-mediated transgenesis, Cre is in fact highly...

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Detalhes bibliográficos
Main Authors: Hans, Stefan, Kaslin, Jan, Freudenreich, Dorian, Brand, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645673/
https://ncbi.nlm.nih.gov/pubmed/19247481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004640
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