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The critical role of ERK in death resistance and invasiveness of hypoxia-selected glioblastoma cells

BACKGROUND: The rapid growth of tumor parenchyma leads to chronic hypoxia that can result in the selection of cancer cells with a more aggressive behavior and death-resistant potential to survive and proliferate. Thus, identifying the key molecules and molecular mechanisms responsible for the phenot...

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Autores principales: Kim, Jee-Youn, Kim, Yong-Jun, Lee, Sun, Park, Jae-Hoon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645423/
https://ncbi.nlm.nih.gov/pubmed/19161638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-27
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