In vitro culture and somatic cell nuclear transfer affect imprinting of SNRPN gene in pre- and post-implantation stages of development in cattle

BACKGROUND: Embryo in vitro manipulations during early development are thought to increase mortality by altering the epigenetic regulation of some imprinted genes. Using a bovine interspecies model with a single nucleotide polymorphism, we assessed the imprinting status of the small nuclear ribonucl...

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Hlavní autoři: Suzuki, Joao, Therrien, Jacinthe, Filion, France, Lefebvre, Rejean, Goff, Alan K, Smith, Lawrence C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645379/
https://ncbi.nlm.nih.gov/pubmed/19200381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-9
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