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Preparation of a semisynthetic vaccine to Streptococcus pneumoniae type 3.

A semisynthetic vaccine to Streptococcus pneumoniae type 3 has been developed. The hexasaccharide [leads to 3)GlcpA beta(1 leads to 4)Glcp beta(1 leads to]3 was isolated from a partial acid hydrolysate of the capsular polysaccharide S3. It was coupled to stearylamine by reductamination with NaCNBH3...

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Publicado en:Infect Immun
Autores principales: Snippe, H, van Dam, J E, van Houte, A J, Willers, J M, Kamerling, J P, Vliegenthart, J F
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1983
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264508/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6642655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.42.2.842-844.1983
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