Years-needed-to-treat to add 1 year of life: a new metric to estimate treatment effects in randomized trials

AIMS: A standard metric to estimate absolute treatment effects is numbers-needed-to-treat (NNT), which implicitly assumes that all benefits reverse at trial-end. However, in-trial survival benefits typically do not reverse until long after trial-end, so that NNT will substantially underestimate life...

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Detalhes bibliográficos
Main Authors: Levy, Wayne C., Mozaffarian, Dariush, Linker, David T., Kenyon, Kenneth W., Cleland, John G.F., Komajda, Michel, Remme, Willem J., Torp-Pedersen, Christian, Metra, Marco, Poole-Wilson, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645057/
https://ncbi.nlm.nih.gov/pubmed/19164422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurjhf/hfn048
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