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Protein kinase C-θ is required for efficient positive selection
Protein kinase C-θ (PKCθ) is critical for TCR initiated signaling in mature T cells, but initial reports found no requirement for PKCθ in thymocyte development. Thymocytes and peripheral T cells utilize many of the same signaling components, and given the significant role of PKCθ in peripheral T cel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645034/ https://ncbi.nlm.nih.gov/pubmed/18802072 |
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