Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9

We cloned a new inhibitor of apoptosis protein (IAP) homolog, SfIAP, from Spodoptera frugiperda Sf-21 cells, a host of insect baculoviruses. SfIAP contains two baculovirus IAP repeat domains followed by a RING domain. SfIAP has striking amino acid sequence similarity with baculoviral IAPs, CpIAP and...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Huang, Qihong, Deveraux, Quinn L., Maeda, Susumu, Salvesen, Guy S., Stennicke, Henning R., Hammock, Bruce D., Reed, John C.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2000
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10677478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.4.1427
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