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Local Phylogeny Mapping of Quantitative Traits: Higher Accuracy and Better Ranking Than Single-Marker Association in Genomewide Scans

We present a new method, termed QBlossoc, for linkage disequilibrium (LD) mapping of genetic variants underlying a quantitative trait. The method uses principles similar to a previously published method, Blossoc, for LD mapping of case/control studies. The method builds local genealogies along the g...

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Detalhes bibliográficos
Main Authors: Besenbacher, Søren, Mailund, Thomas, Schierup, Mikkel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644962/
https://ncbi.nlm.nih.gov/pubmed/19064712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.092643
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