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Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice

Pathogenicity differences among laboratory isolates of the dominant clonal North American and European lineages of Toxoplasma gondii are largely controlled by polymorphisms and expression differences in rhoptry secretory proteins (ROPs). However, the extent to which such differences control virulenc...

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Detalhes bibliográficos
Main Authors: Khan, Asis, Taylor, Sonya, Ajioka, James W., Rosenthal, Benjamin M., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644818/
https://ncbi.nlm.nih.gov/pubmed/19266027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000404
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