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An activating β1 integrin mutation increases conversion of benign to malignant skin tumours
A major challenge is to identify the physiological relevance of cancer-associated genetic polymorphisms. Several changes in the coding sequence of β integrin subunits have now been described in human tumours. One of these, T188Iβ1, was identified as a heterozygous mutation in a poorly differentiated...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644725/ https://ncbi.nlm.nih.gov/pubmed/19190332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3051 |
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