Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

Long-lived memory B cells (B(Mem)) provide an archive of historic Ab responses. By contrast, circulating Abs typically decline once the immunogen is cleared. Consequently, circulating Abs can underestimate the nature of cognate humoral immunity. On the other hand, the B(Mem) pool should provide a co...

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Main Authors: Guan, Yongjun, Sajadi, Mohammad M., Kamin-Lewis, Roberta, Fouts, Timothy R., Dimitrov, Anthony, Zhang, Zhixin, Redfield, Robert R., DeVico, Anthony L., Gallo, Robert C., Lewis, George K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644653/
https://ncbi.nlm.nih.gov/pubmed/19225108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813392106
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