Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

Long-lived memory B cells (B(Mem)) provide an archive of historic Ab responses. By contrast, circulating Abs typically decline once the immunogen is cleared. Consequently, circulating Abs can underestimate the nature of cognate humoral immunity. On the other hand, the B(Mem) pool should provide a co...

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Autori principali: Guan, Yongjun, Sajadi, Mohammad M., Kamin-Lewis, Roberta, Fouts, Timothy R., Dimitrov, Anthony, Zhang, Zhixin, Redfield, Robert R., DeVico, Anthony L., Gallo, Robert C., Lewis, George K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644653/
https://ncbi.nlm.nih.gov/pubmed/19225108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813392106
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