Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infection

Long-lived memory B cells (B(Mem)) provide an archive of historic Ab responses. By contrast, circulating Abs typically decline once the immunogen is cleared. Consequently, circulating Abs can underestimate the nature of cognate humoral immunity. On the other hand, the B(Mem) pool should provide a co...

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Bibliografiske detaljer
Main Authors: Guan, Yongjun, Sajadi, Mohammad M., Kamin-Lewis, Roberta, Fouts, Timothy R., Dimitrov, Anthony, Zhang, Zhixin, Redfield, Robert R., DeVico, Anthony L., Gallo, Robert C., Lewis, George K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644653/
https://ncbi.nlm.nih.gov/pubmed/19225108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813392106
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