Biomarkers of Human Exposure to Acrylamide and Relation to Polymorphisms in Metabolizing Genes

Acrylamide (AA) is formed in heat treated carbohydrate rich foods in the so-called Maillard reaction. AA is readily absorbed in the body and converted to glycidamide (GA) by epoxidation by the CYP2E1 (cytochrome P450 2E) enzyme. Both AA and GA may be detoxified through direct conjunction to glutathi...

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Detaylı Bibliyografya
Asıl Yazarlar: Duale, Nur, Bjellaas, Thomas, Alexander, Jan, Becher, Georg, Haugen, Margaretha, Paulsen, Jan Erik, Frandsen, Henrik, Olesen, Pelle Thonning, Brunborg, Gunnar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Genetic Toxicology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644397/
https://ncbi.nlm.nih.gov/pubmed/19131562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn269
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