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Mutational Analysis of the Stability of the H2A and H2B Histone Monomers

The eukaryotic histone heterodimer H2A-H2B folds through an obligatory dimeric intermediate that forms in a nearly diffusion-limited association reaction in the stopped-flow dead time. It is unclear whether there is partial folding of the isolated monomers before association. To address the possible...

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Detalhes bibliográficos
Main Authors: Stump, Matthew R., Gloss, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644352/
https://ncbi.nlm.nih.gov/pubmed/18976667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.040
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