Reactivation of suppressed RhoB is a critical step for inhibition of anaplastic thyroid cancer growth

Anaplastic thyroid carcinoma (ATC) is a highly aggressive form of the disease for which new therapeutic options are desperately needed. Previously, we showed that the high affinity PPARγ agonist, RS5444, inhibits cell proliferation of ATC cells via induction of the cyclin dependent kinase inhibitor...

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Huvudupphovsmän: Marlow, Laura A., Reynolds, Lisa A., Cleland, Alan S., Cooper, Simon J., Gumz, Michelle L., Kurakata, Shinichi, Fujiwara, Kosaku, Zhang, Ying, Sebo, Thomas, Grant, Clive, McIver, Bryan, Wadsworth, J. Trad, Radisky, Derek C., Smallridge, Robert C., Copland, John A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644344/
https://ncbi.nlm.nih.gov/pubmed/19208833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3718
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