Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis

The recent discovery of fatty acyl-AMP ligases (FAALs) in Mycobacterium tuberculosis (Mtb) provided a new perspective to fatty acid activation dogma. These proteins convert fatty acids to corresponding adenylates, which is an intermediate of acyl-CoA-synthesizing fatty acyl-CoA ligases (FACLs). Pres...

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Autors principals: Arora, Pooja, Goyal, Aneesh, Natarajan, Vivek T, Rajakumara, Eerappa, Verma, Priyanka, Gupta, Radhika, Yousuf, Malikmohamed, Trivedi, Omita A., Mohanty, Debasisa, Tyagi, Anil, Sankaranarayanan, Rajan, Gokhale, Rajesh S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644305/
https://ncbi.nlm.nih.gov/pubmed/19182784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.143
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