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Mice heterozygous for both A(1) and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine

Caffeine is believed to exert its stimulant effects by blocking A(2A) and A(1) adenosine receptors (A(2A)R and A(1)R). Although a genetic knockout of A(2A)R eliminates effects of caffeine, the phenotype of the knockout animal does not resemble that of caffeine treatment. In this study we explored th...

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Detalhes bibliográficos
Main Authors: Yang, Jiang-Ning, Björklund, Olga, Lindström-Törnqvist, Karin, Lindgren, Eva, Eriksson, Therese M., Kahlström, Johan, Chen, Jiang-Fan, Schwarzschild, Michael A., Tobler, Irene, Fredholm, Bertil B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644247/
https://ncbi.nlm.nih.gov/pubmed/19036889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.90971.2008
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