Apolipoprotein E ε4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia

Apolipoprotein ε4 (apoE4) has been strongly linked with Alzheimer's disease (AD) and contributes to several other neurological disorders. We investigated the influence of ε4 allele carrier status on the pattern of gray matter atrophy and disease severity in 51 patients with probable AD and 31 p...

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Autori principali: Agosta, Federica, Vossel, Keith A., Miller, Bruce L., Migliaccio, Raffaella, Bonasera, Stephen J., Filippi, Massimo, Boxer, Adam L., Karydas, Anna, Possin, Katherine L., Gorno-Tempini, Maria Luisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644156/
https://ncbi.nlm.nih.gov/pubmed/19164761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812697106
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