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Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

Migration on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) that does not correlate with formula molecular weights, termed “gel shifting,” appears to be common for membrane proteins but has yet to be conclusively explained. In the present work, we investigate the anomalous gel...

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Detalhes bibliográficos
Main Authors: Rath, Arianna, Glibowicka, Mira, Nadeau, Vincent G., Chen, Gong, Deber, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644111/
https://ncbi.nlm.nih.gov/pubmed/19181854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813167106
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