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Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

Migration on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) that does not correlate with formula molecular weights, termed “gel shifting,” appears to be common for membrane proteins but has yet to be conclusively explained. In the present work, we investigate the anomalous gel...

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Bibliografiske detaljer
Main Authors: Rath, Arianna, Glibowicka, Mira, Nadeau, Vincent G., Chen, Gong, Deber, Charles M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644111/
https://ncbi.nlm.nih.gov/pubmed/19181854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813167106
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