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Mammalian metallopeptidase inhibition at the defense barrier of Ascaris parasite

Roundworms of the genus Ascaris are common parasites of the human gastrointestinal tract. A battery of selective inhibitors protects them from host enzymes and the immune system. Here, a metallocarboxypeptidase (MCP) inhibitor, ACI, was identified in protein extracts from Ascaris by intensity-fading...

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Bibliographic Details
Main Authors: Sanglas, Laura, Aviles, Francesc X., Huber, Robert, Gomis-Rüth, F. Xavier, Arolas, Joan L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644108/
https://ncbi.nlm.nih.gov/pubmed/19179285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812623106
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