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Splenic plasma cells can serve as a source of amyloidogenic light chains

Bone marrow-derived clonal plasma cells, as found in systemic amyloidogenic light chain–associated (AL) amyloidosis, are presumed to be the source of light chains that deposit as fibrils in tissues throughout the body. Paradoxically, people with this disorder, in contrast to multiple myeloma, often...

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Hlavní autoři: Solomon, Alan, Macy, Sallie D., Wooliver, Craig, Weiss, Deborah T., Westermark, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644077/
https://ncbi.nlm.nih.gov/pubmed/19050307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-154484
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