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Chronic intermittent hypoxia impairs heart rate responses to AMPA and NMDA and induces loss of glutamate receptor neurons in nucleus ambiguus of F344 rats

Chronic intermittent hypoxia (CIH), as occurs in sleep apnea, impairs baroreflex-mediated reductions in heart rate (HR) and enhances HR responses to electrical stimulation of vagal efferent. We tested the hypotheses that HR responses to activation of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate...

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Detalhes bibliográficos
Main Authors: Yan, Binbin, Li, Lihua, Harden, Scott W., Gozal, David, Lin, Ying, Wead, William B., Wurster, Robert D., Cheng, Zixi (Jack)
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643981/
https://ncbi.nlm.nih.gov/pubmed/19020286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90412.2008
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