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New tricks for old NODs

Recent work has identified the human NOD-like receptor NLRX1 as a negative regulator of intracellular signaling leading to type I interferon production. Here we discuss these findings and the questions and implications they raise regarding the function of NOD-like receptors in the antiviral response...

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Detalles Bibliográficos
Main Authors: Pietras, Eric M, Cheng, Genhong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643928/
https://ncbi.nlm.nih.gov/pubmed/18466630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-4-217
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