Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-κB signaling

We have previously demonstrated that in a rat model of trauma-hemorrhage (T-H), glucosamine administration during resuscitation improved cardiac function, reduced circulating levels of inflammatory cytokines, and increased tissue levels of O-linked N-acetylglucosamine (O-GlcNAc) on proteins. The mec...

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Autori principali: Zou, Luyun, Yang, Shaolong, Champattanachai, Voraratt, Hu, Shunhua, Chaudry, Irshad H., Marchase, Richard B., Chatham, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643896/
https://ncbi.nlm.nih.gov/pubmed/19098112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01025.2008
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