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Dietary K regulates ROMK channels in connecting tubule and cortical collecting duct of rat kidney

The activity of ROMK channels in rat kidney tubule cells was assessed as tertiapin-Q (TPNQ)-sensitive current under whole cell clamp conditions. With an external K(+) concentration of 5 mM and an internal K(+) concentration of 140 mM and the membrane potential clamped to 0 mV, TPNQ blocked outward c...

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Bibliografiske detaljer
Main Authors: Frindt, Gustavo, Shah, Anish, Edvinsson, Johan, Palmer, Lawrence G.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643862/
https://ncbi.nlm.nih.gov/pubmed/19036846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90527.2008
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