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Expression of the A56 and K2 Proteins Is Sufficient To Inhibit Vaccinia Virus Entry and Cell Fusion

Many animal viruses induce cells to fuse and form syncytia. For vaccinia virus, this phenomenon is associated with mutations affecting the A56 and K2 proteins, which form a multimer (A56/K2) on the surface of infected cells. Recent evidence that A56/K2 interacts with the entry/fusion complex (EFC) a...

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Bibliographic Details
Main Authors: Wagenaar, Timothy R., Moss, Bernard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643798/
https://ncbi.nlm.nih.gov/pubmed/19036815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01684-08
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