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Gene Regulation and Functional Alterations Induced by Kaposi's Sarcoma-Associated Herpesvirus-Encoded ORFK13/vFLIP in Endothelial Cells

Kaposi's sarcoma (KS) is an angioproliferative inflammatory disorder induced by endothelial cell infection with the KS-associated herpesvirus (KSHV). ORFK13/vFLIP, one of the KSHV genes expressed in KS, encodes a 188-amino-acid protein which binds to the Iκb kinase (IKK) complex to activate NF-...

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Autori principali: Sakakibara, Shuhei, Pise-Masison, Cynthia A., Brady, John N., Tosato, Giovanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643737/
https://ncbi.nlm.nih.gov/pubmed/19091861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01871-08
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