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Structural Characterization of the Rous Sarcoma Virus RNA Stability Element

In eukaryotic cells, an mRNA bearing a premature termination codon (PTC) or an abnormally long 3′ untranslated region (UTR) is often degraded by the nonsense-mediated mRNA decay (NMD) pathway. Despite the presence of a 5- to 7-kb 3′ UTR, unspliced retroviral RNA escapes this degradation. We previous...

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Bibliografiske detaljer
Main Authors: Weil, Jason E., Hadjithomas, Michalis, Beemon, Karen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643715/
https://ncbi.nlm.nih.gov/pubmed/19091866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02113-08
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