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The Schistosoma mansoni Protein Sm16/SmSLP/SmSPO-1 Assembles into a Nine-Subunit Oligomer with Potential To Inhibit Toll-Like Receptor Signaling

The Sm16/SmSLP/SmSPO-1 (Sm16) protein is secreted by the parasite Schistosoma mansoni during skin penetration and has been ascribed immunosuppressive activities. Here we describe the strategy behind the design of a modified Sm16 protein with a decreased aggregation propensity, thus facilitating the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brännström, Kristoffer, Sellin, Mikael E., Holmfeldt, Per, Brattsand, Maria, Gullberg, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643650/
https://ncbi.nlm.nih.gov/pubmed/19124604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01126-08
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