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The H35A Mutated Alpha-Toxin Interferes with Cytotoxicity of Staphylococcal Alpha-Toxin

Staphylococcal alpha-toxin is an important virulence factor for Staphylococcus aureus to cause severe infections. In this study, we explored whether the toxoid of alpha-toxin may be utilized to block the toxicity of wild-type alpha-toxin. We created a series of H35A mutated alpha-toxin expression st...

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Detalhes bibliográficos
Main Authors: Liang, Xudong, Yan, Meiying, Ji, Yinduo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643624/
https://ncbi.nlm.nih.gov/pubmed/19103771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00920-08
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