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Tritium Suicide Selection Identifies Proteins Involved in the Uptake and Intracellular Transport of Sterols in Saccharomyces cerevisiae

Sterol transport between the plasma membrane (PM) and the endoplasmic reticulum (ER) occurs by a nonvesicular mechanism that is poorly understood. To identify proteins required for this process, we isolated Saccharomyces cerevisiae mutants with defects in sterol transport. We used Upc2-1 cells that...

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Bibliographic Details
Main Authors: Sullivan, David P., Georgiev, Alexander, Menon, Anant K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643606/
https://ncbi.nlm.nih.gov/pubmed/19060182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00135-08
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