Bacterin That Induces Anti-OspA and Anti-OspC Borreliacidal Antibodies Provides a High Level of Protection against Canine Lyme Disease

Groups of 15 laboratory-bred beagles were vaccinated and boosted with either a placebo or adjuvanted bivalent bacterin comprised of a traditional Borrelia burgdorferi strain and a unique ospA- and ospB-negative B. burgdorferi strain that expressed high levels of OspC and then challenged with B. burg...

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Hlavní autoři: LaFleur, Rhonda L., Dant, Jennifer C., Wasmoen, Terri L., Callister, Steven M., Jobe, Dean A., Lovrich, Steven D., Warner, Thomas F., Abdelmagid, O., Schell, Ronald F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Veterinary Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643534/
https://ncbi.nlm.nih.gov/pubmed/19052162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00373-08
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